The gut is getting a lot of attention these days. Some foods such as gluten (from wheat) and lectins (from some vegetables) can cause leaky gut and leaky gut has been implicated inflammatory bowel disease, type 1 diabetes, asthma, multiple sclerosis, schizophenia and cancer.
I wanted to create a web site where I could keep track of and share some of the interesting health and diet content that I have found during the past few years. In order to set this up I needed a unique web site and domain name. While pondering this I glanced at a poster that is on a wall near my computer. This poster talks about zonulin and tight junctions. Zonulin is a protein that that can open tight junctions in the intestine and the blood brain barrier. When these junctions are open you have a leaky gut (and leaky blood brain barrier). As a result pathogens and the like can get into your system which then can cause immune responses including inflammation. This can result in several different health problems. Although this web site is not focused on leaky gut I thought that Zonulin Tight Junction would be a good web site name. The video below goes into this in more detail
This video by Alessio Fasano goes into more detail on gluten, zonulin and leaky gut. A leaky gut results in inflammation and this can cause autoimmune issues such as arthritis, asthma, type 1 diabetes, heart disease and cancer.
Going on a Paleo Ketogenic diet decreases gut permeability which helps to reduce auto-immune disease symptoms.
The first part of this video from down under talks about a down under problem. If you are suffering from irregularity you eat more fiber ... right? Here we see Paul Mason debunkng a well known but incorrect medical prescription. Fyi ... the worse case of constipation I have ever had was after eating a bowl of "Fiber One" cereal.
This video is a good summary on gluten. I should mention here that when you go low carb you automatically reduce your gluten intake. A lot of the low carb benefits that you see could be due to this gluten reduction.
I thought that the book "The Plant Paradox" went a bit overboard on classifying lectins as the devil. After seeing this discussion with Paul Mason I am having second thoughts.
Dr. Davis wrote the book "Wheat Belly" in 2011. It was a best seller within one month. It could be that everyone has some degree of gluten sensitivity.
This Paul Mason presentation is sort of scary. It makes you want to go carnivore.
A good book that I read on this subject is called "Fiber Menace" by Konstantin Monastyrsky. This is a video that he did. He seems like someone on late night television who is trying to sell you something but I think a lot of what he says is backed up by the science.